Health Areas › Gastrointestinal and Liver Disorders

Gastrointestinal and Liver Disorders

Area 10 in the list of seventeen published by the Saudi National Institute of Health in June 2025. Order follows SNIH's published list: that number is SNIH's own position for the area; it is not a ranking by this site and it says nothing about how much research this area should receive.

This area is matched to research by its subject headings, Digestive System Diseases (C06), and to disease burden by the WHO cause-to-area table v0.4. The two line up well enough here for the research-share-to-burden-share ratio to be shown, with the differences named: a close match.

A paper or study can count in more than one area. Areas as published by the Saudi National Institute of Health (SNIH), June 2025, applied to 2021–2025 retrospectively, for description only. A Saudi affiliation is not the same as research on the Saudi population.

Close match. The area and its WHO causes line up well enough to show the research-share-to-burden-share ratio, with the differences named.

Close match

Order follows SNIH's published list: area 10 of seventeen.

Coverage Of The Underlying Corpus · 2021–2025

On the same selection, before the area filter. Papers without MeSH terms stay in this coverage line; they are never in any area or in the grey row. It describes the corpus, not how completely this area’s research is captured.

Papers without MeSH terms cannot be assigned to any area, so this profile is never a complete count of the area’s research, and it does not measure how completely that research is captured. Coverage: records captured by the named sources that meet the published eligibility rules; coverage is not exhaustive.

Eligible publications with MeSH terms

60.6%

PubMed with OpenAlex · 2021–2025

Eligible publications matched to any area

41.3%

PubMed with OpenAlex · 2021–2025

The Burden This Area Carries

Burden Share & Research Share

Burden: WHO Global Health Estimates, 2023 · research: 2021–2025

Share of national disease burden

Source: WHO Global Health Estimates, 2023, through the WHO cause-to-area table v0.4. All-age disability-adjusted life years for one named year.

4.7%

WHO · 2023

Research share among MeSH-indexed eligible publications

Eligible publications in this area, 2021–2025, divided by all eligible publications with MeSH terms in the same selection, before the area filter. Shares across the seventeen areas do not sum to 100%.

6.2%

of the eligible publications with MeSH terms · 2021–2025

Research-share-to-burden-share ratio

Shown because this area is a close match. A ratio of 1 means equal shares under these definitions; it does not establish adequate research effort or funding, and it carries no judgement about what the right figure would be.

1.34

Recorded Research

Three Counts, Never One Total

Papers and registrations are counted separately, never added together.

A paper, a clinical trial and an observational registration are different kinds of record, so this area carries three separate counts. They are never added together.

Papers and registrations are different kinds of record. They are counted separately and never added together, anywhere on this site. Counts describe recorded activity; they do not assess quality, benefit or performance.

Registrations are ClinicalTrials.gov records; a listed site doesn't prove recruitment in Saudi Arabia.

Journals that follow ICMJE policy require clinical trials to be registered before enrolment begins, in ClinicalTrials.gov or another accepted registry; observational studies have no such requirement, so registered observational studies are a small, selective part of observational research. These figures count studies recorded in ClinicalTrials.gov; they do not measure total research volume, study completion or financial investment.

Trials and observational studies are those listing a Saudi site. A listed site does not prove that participants were recruited in Saudi Arabia. Withdrawn studies and expanded-access records are not counted.

Publications

PubMed and OpenAlex · research-related papers with a Saudi affiliation carrying Digestive System Diseases (C06) · 2021–2025

PubMed with OpenAlex · 2021–2025 provisional

Clinical trials

ClinicalTrials.gov · interventional, listing a Saudi site · 2021–2025

ClinicalTrials.gov · 2021–2025 provisional

Observational studies

ClinicalTrials.gov · observational registrations listing a Saudi site · 2021–2025

ClinicalTrials.gov · 2021–2025 provisional

Publications By Year

Research-related papers in this area, by year of earliest publication. The axis starts at zero and ends at 1,000.

2021
2022
2023
2024
2025 provisional
Publications By Study Group

Research-related papers in this area, 2021–2025, in the five study groups. The axis starts at zero and ends at 2,000.

Interventional
Observational
Evidence synthesis
Laboratory and animal
Other designs
Clinical Trials By Phase

Trials in this area, 2021–2025. A trial registered across two phases counts in both. The axis starts at zero and ends at 10.

Early phase 1 0
Phase 1 0
Phase 2
Phase 3
Phase 4 0
Not applicable
Clinical Trials By Recruitment Status

Trials in this area, 2021–2025, by status as the registry records it on the day ClinicalTrials.gov processed the data. The axis starts at zero and ends at 10. Statuses open largest first.

Completed
Recruiting
Active, not recruiting
Unknown
Enrolling by invitation 0
Not yet recruiting 0
Suspended 0
Terminated 0
Observational Studies By Recruitment Status

Observational studies in this area, 2021–2025, by status as the registry records it. The axis starts at zero and ends at 5. Statuses open largest first.

Completed
Recruiting
Terminated
Unknown
Active, not recruiting 0
Enrolling by invitation 0
Not yet recruiting 0
Suspended 0

Industry

Industry In This Area

The area's three counts narrowed to industry: research papers coded industry-involved, industry-led clinical trials and industry-led observational studies, each with its share of the area's own count. They are three kinds of record and are never added together.

Industry in papers comes from each paper's own industry code; industry in registrations comes from the lead sponsor. They are different measures of different records and are never combined.

Industry in registrations means a lead sponsor that is a company making or selling health products (drugs, vaccines, biotechnology, devices, diagnostics, health software or medical nutrition), as the industry guide defines it in its section two, or a contract research organisation with such a company listed as collaborator. Hospital groups and other providers that ClinicalTrials.gov labels “industry” are not counted. Withdrawn studies are not counted.

Journals that follow ICMJE policy require clinical trials to be registered before enrolment begins, in ClinicalTrials.gov or another accepted registry; observational studies have no such requirement, so registered observational studies are a small, selective part of observational research. These figures count studies recorded in ClinicalTrials.gov; they do not measure total research volume, study completion or financial investment.

Counts describe recorded activity; they do not measure investment, quality or performance.

Industry involvement in papers is a lower bound.

Industry involvement is identified from the paper's own record and registration; it does not establish financial investment and is a lower bound.

Industry-involved publications

3% of the 2,545 research papers in the area

PubMed with OpenAlex · 2021–2025 provisional

Industry-led clinical trials

53% of the 17 clinical trials in the area

ClinicalTrials.gov · 2021–2025 provisional

Industry-led observational studies

29% of the 7 observational studies in the area

ClinicalTrials.gov · 2021–2025 provisional

Companies

Companies Leading Studies In This Area

Every company credited with at least one industry-led clinical trial or observational study in this area, 2021–2025, with both counts: two counts, never one total. Each study is credited to one company, exactly as the industry-led counts decide it: its lead sponsor or, for a contract research organisation's study, its company collaborator listed in the registration. So the companies' studies add up to the area's industry-led counts. A study in several areas counts in each. Names are shown as registered, with no grouping into parent companies.

There is no rank column. The list opens with the most clinical trials, ties A–Z. Every count above zero opens its records.

Only studies listing a Saudi site are counted. Industry in registrations means a lead sponsor that is a company making or selling health products (drugs, vaccines, biotechnology, devices, diagnostics, health software or medical nutrition), as the industry guide defines it in its section two, or a contract research organisation with such a company listed as collaborator. Hospital groups and other providers that ClinicalTrials.gov labels “industry” are not counted. Withdrawn studies are not counted.

Journals that follow ICMJE policy require clinical trials to be registered before enrolment begins, in ClinicalTrials.gov or another accepted registry; observational studies have no such requirement, so registered observational studies are a small, selective part of observational research. These figures count studies recorded in ClinicalTrials.gov; they do not measure total research volume, study completion or financial investment.

The counts describe registered activity; they do not measure investment, quality or performance.

Showing 2021–2025 provisional

Registrations are ClinicalTrials.gov records; a listed site doesn't prove recruitment in Saudi Arabia.

A listed site does not prove that participants were recruited in Saudi Arabia. Withdrawn studies and expanded-access records are not counted.

Companies Credited With Industry-Led Studies In Gastrointestinal and Liver Disorders, 2021–2025.
CompanyClinical trialsObservational studies
AbbVie 0
AstraZeneca
Boehringer Ingelheim 0
GlaxoSmithKline 0
Merck Sharp & Dohme LLC 0
Orphalan 0

Institutions

Institutions In This Area

Every institution on the approved list with at least one research-related publication, clinical trial or observational study in this area, 2021–2025. Three counts, never one total: a paper, a clinical trial and an observational registration are different kinds of record.

They are counted exactly as on Institutions & Clusters: publications in full; a parent institution's row also counts its units' papers and studies, so rows overlap and are never added together; clinical trials and observational studies count registrations listing the institution as a site, and a listed site does not prove that participants were recruited there. Institutions are named as OpenAlex records them.

There is no rank column. The list opens with the most publications, ties A–Z; the switch orders it by clinical trials, observational studies or A–Z. Every count above zero opens its records. No citation measure is given here.

53 of the area's 2,545 research papers have no Saudi institution identified and count in no institution · PubMed with OpenAlex · 2021–2025 provisional

Institutions With Research In Gastrointestinal and Liver Disorders, 2021–2025.
InstitutionPublicationsClinical trialsObservational studies
King Saud University 0
King Abdulaziz University 0 0
King Faisal Specialist Hospital & Research Centre
King Khalid University 0 0
Princess Nourah bint Abdulrahman University 0 0
Umm al-Qura University 0
Taif University 0 0
Prince Sattam Bin Abdulaziz University 0 0
King Saud bin Abdulaziz University for Health Sciences 0 0
Qassim University 0 0
Alfaisal University 0 0
Jazan University 0 0
Jouf University 0 0
King Abdullah International Medical Research Center 0 0
National Guard Health Affairs 0 0
University of Jeddah 0 0
Imam Abdulrahman Bin Faisal University 0 0
King Faisal University 0 0
University of Tabuk 0 0
Taibah University 0 0
King Fahd Medical City 0 0
Shaqra University 0 0
King Abdulaziz Medical City
King Saud Medical City 0 0
Imam Mohammad ibn Saud Islamic University 0 0
University of Bisha 0 0
Almaarefa University 0 0
Ministry of Health 0 0
Batterjee Medical College 0 0
Majmaah University 0 0
King Khalid University Hospital 0 0
Najran University 0 0
Northern Border University 0 0
King Abdul Aziz University Hospital 0
University of Ha'il 0 0
Al Baha University 0 0
King Fahad Specialist Hospital (location not recorded) 0 0
Riyadh Armed Forces Hospital 0 0
King Abdullah University of Science and Technology 0 0
King Fahd Hospital of the University 0 0
King Abdulaziz City for Science and Technology 0 0
Sulaiman Al Rajhi Colleges 0 0
University of Hafr Al-Batin 0 0
Jeddah First Health Cluster 0 0
King Khaled Hospital (location not recorded) 0 0
Saudi Aramco (Saudi Arabia) 0 0
Saudi Aramco Medical Services Organization 0 0
King Abdulaziz Hospital (Jeddah First Health Cluster) 0 0
King Abdullah Medical City 0
Asir Central Hospital 0 0
Fakeeh College for Medical Sciences 0 0
Security Forces Hospital 0 0
King Fahd Armed Forces Hospital 0 0
Saudi Electronic University 0 0
Armed Forces Hospital (location not recorded) 0 0
Dar Al Uloom University 0 0
Ibn Sina National College for Medical Studies 0 0
King Fahd Military Medical Complex 0 0
Islamic University of Madinah 0 0
Prince Mohammad bin Fahd University 0 0
Riyadh Elm University 0 0
King Fahad Hospital Jeddah 0 0
Maternity and Children's Hospital (location not recorded) 0 0
Saudi Food and Drug Authority 0 0
Soliman Fakeeh Hospital 0 0
International Medical Center in Jeddah 0 0
King Fahd University of Petroleum and Minerals 0 0
Prince Mohammed bin Abdulaziz Hospital 0 0
Prince Sultan University 0 0
Qatif Central Hospital 0 0
Dammam Central Hospital 0 0
East Jeddah Hospital 0 0
King Fahad Hospital Hufūf 0 0
King Salman Center for Disability Research 0 0
Naif Arab University for Security Sciences 0 0
Prince Sultan Military College of Health Sciences 0 0
Research and Innovation Institute (location not recorded) 0 0
Al-Farabi College 0 0
Al-Ghad International Health Sciences Colleges 0 0
Armed Forces Hospital in Wadi Al-Dawasir 0 0
Buraydah Colleges 0 0
Dar Al-Hekma University 0 0
Fahd bin Sultan University 0 0
King Fahad Central Hospital (location not recorded) 0 0
Ministry of Defense 0 0
Mohammed Almana College for Medical Sciences 0 0
Armed Forces Hospital Southern Region 0 0
Effat University 0 0
Hera General Hospital 0 0
King Abdulaziz Hospital (location not recorded) 0 0
King Khaled Eye Specialist Hospital 0 0
Ministry of Education 0 0
North West Armed Forces Hospital 0 0
Onaizah Colleges 0 0
Prince Mohammad Bin Salman College of Business and Entrepreneurship 0 0
Saudi Center for Disease Prevention and Control 0 0
Saudi Water Authority 0 0
University of Business and Technology 0 0

Clinical Trials

Clinical Trials By Intervention Type

The area's clinical trials, 2021–2025, by ClinicalTrials.gov's intervention type, with the industry-led part. A trial with several intervention types counts in each, so the bars are never added together and can sum to more than the area's 17 trials. “Other” is the registry's own type; it comes last, as “Not recorded” would. The list opens largest first, ties A–Z. Each count above zero opens its records. Observational studies are not shown by type.

The axis starts at zero and ends at 10.

All trials Industry-led trials

Drug ·
Procedure ·
Combination Product ·
Diagnostic Test · 0
Dietary Supplement · 0
Other ·

ClinicalTrials.gov · 2021–2025 provisional

National Health Facts · Saudi Arabia

Gastrointestinal and Liver Disorders: National Health Facts

National health facts checked against their sources: 4 November 2026 to 5 November 2026.

Each card names its source in short; its ⓘ gives the full source. The full view below holds every fact with its full source.

Estimate. Estimated or modelled by its source, not counted directly.

National figures for all residents unless stated.

At A Glance

17%

of this area's burden is from colorectal cancer, with about 1,700 deaths in 2023 (also counted in Cancer)

Estimate WHO · 2023

Estimate WHO Global Health Estimates, 2023 · 2023 · also counted in Cancer

About 1,750

deaths from liver cancer and cirrhosis in 2023

Estimate WHO · 2023

Estimate WHO Global Health Estimates, 2023 · 2023

0.0%

of children under 5 have hepatitis B infection (2024), WHO's modelled estimate exactly as WHO shows it

Estimate WHO · 2024

Estimate WHO hepatitis dashboard, Saudi Arabia · 2024 · children under 5, HBsAg prevalence, modelled · 0.0 to 0.0, uncertainty interval

Show Health Facts & SourcesHide Health Facts & Sources

Burden

Lost healthy life by condition within this area, 2023 (WHO estimates, WHO causes matched to the area by the project's cause table v0.4). The area's share of national burden appears in the profile's burden comparison lower down. DALYs are the years of healthy life lost to illness, disability or early death.

Colon and rectum cancers 17%
Diarrhoeal diseases 12%
Liver cancer 10%
Gallbladder and biliary diseases 8%
Pancreatic cancer 7%
Cirrhosis of the liver 7%

Source: WHO Global Health Estimates, 2023

  • 1,691 Colon and rectum cancersWHO Global Health Estimates, 2023 · 2023
  • 1,176 Liver cancerWHO Global Health Estimates, 2023 · 2023
  • 780 Pancreatic cancerWHO Global Health Estimates, 2023 · 2023
  • 575 Cirrhosis of the liverWHO Global Health Estimates, 2023 · 2023

Sources Of These Facts

About These Figures

How This Area Is Matched

A paper belongs to this area when any of its subject headings is one of the area's headings or sits beneath it. Registered studies use the same headings, applied to the conditions the registry records. Only records carrying subject headings can be assigned at all, and coverage is reported for every selection.

What This Page Does Not Say

Nothing here assesses quality, benefit or performance, and no figure on it should be read as a target. The research-share-to-burden-share ratio compares two shares; it does not establish that research in this area is too much, too little or correctly aimed. Counts describe what is recorded, which is not the same as what was done.

Where The Figures Come From

Publications from PubMed matched with OpenAlex; trials and observational studies from ClinicalTrials.gov. Area assignment follows the SNIH 17-area research dictionary v1.2; burden follows the WHO cause-to-area table v0.4. Both are published in full on the methods page.

* Not final: counts for these years usually rise at later updates, as many studies are registered after they start and recent papers are still being added. On this page: trials and publications 2025; observational studies 2024–2025.